Biochemistry

A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules.

The ENZYME database is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB), and it contains the following data for each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided: EC number, Recommended name, Alternative names (if any), Catalytic activity, Cofactors (if any), Pointers to the Swiss-Prot protein sequence entrie(s) that correspond to the enzyme (if any), Pointers to human disease(s) associated with a deficiency of the enzyme (if any).

KEGG LIGAND contains our knowledge on the universe of chemical substances and reactions that are relevant to life. It is a composite database consisting of COMPOUND, GLYCAN, REACTION, RCLASS, and ENZYME databases, whose entries are identified by C, G, R, RC, and EC numbers, respectively. ENZYME is derived from the IUBMB/IUPAC Enzyme Nomenclature with annotation of reactions and sequences. All the other databases are internally developed and maintained.

We study biomolecular reactions that convert electrochemical energy into chemical bonds of reduced products. This research advances the development of enzyme-based and microbial-based systems for the production of energy compounds and carriers.

The NDB contains information about experimentally-determined nucleic acids and complex assemblies. Use the NDB to perform searches based on annotations relating to sequence, structure and function, and to download, analyze, and learn about nucleic acids.

Proteopedia's mission is to "collect, organize and disseminate structural and functional knowledge about protein, RNA, DNA, and other macromolecules, and their assemblies and interactions with small molecules, in a manner that is relevant and broadly accessible to students and scientists."

The Protein Data Bank (PDB) was established as the 1st open access digital data resource in all of biology and medicine (Historical Timeline). It is today a leading global resource for experimental data central to scientific discovery.

The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

General industrial hygiene information on several hundred chemicals/classes. Presents key information: NIOSH recommended exposure limits, OSHA permissible exposure limits, and NIOSH immediately dangerous to life and health values (IDLH)--with linkouts to these databases. Also physical properties, personal protection recommendations, incompatibilities and reactivities, exposure routes, symptoms and more.

Rapid access to internationally peer reviewed information on chemicals commonly used throughout the world, which may also occur as contaminants in the environment and food. It consolidates information from a number of intergovernmental organizations whose goal it is to assist in the sound management of chemicals.

View a table displaying various biochemical properties of all 20 amino acids, view structural views and detailed properties of a given amino acid, Using data from the BLOSUM62 matrix, view a list of amino acids ranked by how often they substitute for a given amino acid, and Interactively discover what amino acid substitutions result from selected codon mutations, Using data from NCBI curated CD records, explore functional sites within proteins in which a given amino acid plays a pivotal part, Using Entrez Structure, retrieve 3D protein structures containing a given amino acid as a ligand.

Entrez is a molecular biology database system that provides integrated access to nucleotide and protein sequence data, gene-centered and genomic mapping information, 3D structure data, PubMed MEDLINE, and more. The system is produced by the National Center for Biotechnology Information (NCBI) and is available via the Internet. Entrez covers over 20 databases including the complete protein sequence data from PIR-International, PRF, Swiss-Prot, and PDB and nucleotide sequence data from GenBank that includes information from EMBL and DDBJ.

The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. Protein sequences are the fundamental determinants of biological structure and function.

The PubChem BioAssay Database contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure.

The PubChem Substance Database contains descriptions of samples, from a variety of sources, and links to biological screening results that are available in PubChem BioAssay. If the chemical contents of a sample are known, the description includes links to PubChem Compound.

A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM) at the U.S. National Institutes of Health, is a leader in the field of bioinformatics; it studies computational approaches to fundamental questions in biology and provides online delivery of biomedical information and bioinformatics tools. NCBI hosts approximately 40 online literature and molecular biology databases—including PubMed, PubMed Central, and GenBank—that serve millions of users around the world.

The PubChem Compound Database contains validated chemical depiction information provided to describe substances in PubChem Substance. Structures stored within PubChem Compounds are pre-clustered and cross-referenced by identity and similarity groups.

Originally this online resource was created by Robert Husted at Los Alamos National Laboratory during his time as a Graduate Research Assistant, circa 1992. It was given a face lift during 2002/2003 by Mollie Boorman, then a student working at the Laboratory. In 2011, it was again re-designed and updated by Maida Trujillo of the Chemistry Division web team with technical and writing assistance from Dave Hobart and Josh Smith, both of Chemistry Division.

The Royal Society of Chemistry's interactive periodic table features history, alchemy, podcasts, videos, and data trends across the periodic table. Click the tabs at the top to explore each section. Use the buttons above to change your view of the periodic table and view Murray Robertson’s stunning Visual Elements artwork. Click each element to read detailed information.